Nourishing the ecs will maintain balance | homeostasis

Endocannabinoids & ECS Receptors

In order to understand what the ECS is, it’s helpful to imagine the process of how it works.

Take pain, for example. 

Let’s imagine a runner jogging on an intense training session. The runner may experience a level of pain towards the end of the training session.

Once the run is over, the immediate pain isn’t as necessary anymore so the central nervous system (CNS) recruits enzymes to slow down and stop the pain signals. These enzymes then create special molecules called endocannabinoids, primarily anandamide and 2-AG, to acheive the "runners high" feeling.

(AEA) Anandamide

Commonly referred to as the “bliss molecule,” anandamide plays a key role in the regulation of mood and emotion. Low anandamide levels are linked to depression, anxiety, and schizophrenia. Many of the prescription medications used to treat pain and depression increase levels of anandamide.

2-AG (2-Arachidonoylglycerol)
Research shows that one of the main functions of 2-AG is to reduce inflammation while regulating other essential functions of the immune system. Like anandamide, 2-AG is involved in the regulation of mood, emotion, and pain perception, while also playing a role in memory, reproductive health, and sleep cycle regulation.

These endocannabinoids are messengers of sorts, but ones that only activate certain cells — kind of like a key that only opens a certain type of lock. 

These “locks” are actually receptors that sit on the cells throughout the body. The main ones are CB1 and CB2. (CB stands for cannabinoid receptor.) 

In the runner's case, the enzymes created endocannabinoids, which activated the right receptors that told cells in the runner's body to start relieving pain.  This process actually happens in split seconds. 

Once the endocannabinoids have done their job, another group of enzymes shows up to break them down.


millions upon millions of ECS Receptors

CB1 Receptors

CB1 Receptors

CB1 Receptors


CB1 receptors are found throughout the body, with the highest concentrations found in the brain and spinal cord. The CB1 receptors in the hypothalamus regulate metabolism, while CB1 receptors in the amygdala are responsible for regulating emotional response. CB1 receptors are also abundant in nerve endings.

CB2 Receptors

CB1 Receptors

CB1 Receptors


CB2 receptors are also found throughout the body, they are concentrated most within the peripheral nervous system — the nerves extending from the brain and spinal cord to other areas of the body. That means CB2 receptors regulate organ function and muscle movement. CB2 receptors also play a role in the immune system. When activated, CB2 receptors reduce inflammation.


Nourishing your ecs

Everyday changes in your life produces specific responses in your ECS. Endocannabinoid deficiency leads to increased conditions and contributes to conditions/ailments in the body. 

To name a few:

  • Stress-induced anxiety 
  • IBS 
  • Mood 
  • Pain 
  • Sleep disruption 

And much more!  

We highly recommend our Whole Plant Full Spectrum Extracts as a baseline in you and your pet's daily regimen.

Begin your regimen.

Brady's Calming Pack is great because it offers variations to properly feed your Endocannabinoid System.

Consultations are free.